Neural stem cells (NSC) that express Gli1 migrate to sites of demyelination where they differentiate into oligodendrocytes that remyelinate nerve axons, and also say NSCs expressing and not NSCs that express. Inhibition of Gli1 was shown to enhance this phenomenon and improve the clinical signs and remyelination in several in vivo models.

link to Glixogen page

Prof. James Salzer, MD, PhD – Inventor

Yair Fisher, PhD – CSO