Ramino-Bio is developing treatments for cardiometabolic diseases by enhancing branched-chain amino acid (BCAA) catabolism.

Scientific approach

Chronically elevated levels of circulating BCAAs are known to be a propagating factor for cardiac hypertrophy, muscle lipid accumulation, hepatic lipid storage, and glycemia, which contribute to various metabolic disorders. Ramino-Bio is developing a drug for lowering elevated BCAA levels.

link to Ramino Bio page

Indications

 Maple syrup urine disease, Heart failure with preserved ejection fraction

Team

Prof. Yibin Wang, Inventor

Dorit Cohen-Carmon, PhD, CSO

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